How to delete blank at end of multi-line & how to delete multi-line str In the beginning

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Hello, I have two questions, 1. how to delete blank at end of multi-line; 2. how to delete multi-line str In the beginning, for example:

1.#!/usr/bin/env python  
2.from myThread import MyThread  
3.from time import ctime, sleep  
4.def fib(x):  
5.sleep(0.005)

1. I want to delete multi-line blank at end of line,
2. I want to delete multi-line str In the beginning, like: 1. 2. 3. at front of line, thanks very much.